Varalakshmi Manchana, PhD
Associate Professor, University of Hyderabad, India
Biography
Varalakshmi Manchana working as an Associate Professor in the School of Medical Sciences at University of Hyderabad, India. Intervention. Her research interests are geing and Health, Active & Healthy Ageing, Sleep and Pain connections with Mental and Cognitive Health, Ageing-Nutrition and Disability, Fall risk in Ageing, Child Injuries, Moral Resilience in Health professionals, Adolescent wellbeing, Socio Behavioural Interventions for NCDs, Sleep and Pain, Primary care, Women and gender
health. She started her Professional career in 1993, with 10 years of clinical experience to her credit; her teaching career is since 2005 as Lecturer, worked in various capacities like Assistant Professor, Vice-Principal, and Principal before joining the School of Medical Sciences, University of Hyderabad in November 2010. Dr.Manchana is engaged in teaching for UG, Master nursing programs, and teaches MPH program and supervises PhD in Health Sciences (Nursing and Public health) scholars.
Dr.Manchana developed age sensitive physical exercise (HAAEP-PACE) program for functional health and fall prevention in ageing population. She is recipient of the International fellowship for senior Biomedical Scientists (ICMR, 2022-2023), awarded international faculty mobility program, received international program development grant (2018) and conducted “India Ageing Study” pilot research. She is also recipient of extramural research grants to conduct research on Child Injuries and Health and Social status in QOL of older population by ICMR and ICSSR. Her current research is on ‘Fall risk Prevention for functional health and Cognition in Ageing population’ funded by the Institution of Eminence grant. She has presented her work in the national and international conferences of various countries and published 22 research papers, three book chapters in international indexed journals and ten articles.
Publications
1. Lin, F., Lin, E., Anekoji, M., Ichim, T. E., Hu, J., Marincola, F. M., Jones, L., Kesari, S., & Ashili, S. (2023, November 18). Advancing personalized medicine in brain cancer: exploring the role of mRNA vaccines. Journal of Translational Medicine. https://doi.org/10.1186/s12967-023-04724-0
​
2. Manikkath, J., Manikkath, A., Lad, H., Vora, L. K., Mudgal, J., Shenoy, R. R., Radhakrishnan, R., & Ashili, S. (2024 January 10). Nanoparticle-mediated active and passive drug targeting in oral squamous cell carcinoma: Current trends and advances. Nanomedicine. https://doi.org/10.2217/nnm-2023-0247
​
3. Dhas, Y., Arshad, N., Biswas, N., Jones, L., & Ashili, S. (2023, September 20). MicroRNA-21 Silencing in Diabetic Nephropathy: Insights on Therapeutic Strategies. Biomedicines. https://doi.org/10.3390/biomedicines11092583
​
4. Darji, J., Biswas, N., Jones, L., & Ashili, S. (2023, August 24). Handling missing data in the time-series data from wearables. IntechOpen eBooks. https://doi.org/10.5772/intechopen.1002536
​
5. Datta, S., Lin, F., Jones, L., Pingle, S. C., Kesari, S., & Ashili, S. (2023, July 1). Traumatic brain injury and immunological outcomes: the double-edged killer. Future Science OA. https://doi.org/10.2144/fsoa-2023-0037
6. Biswas, N., Chakrabarti, S., Jones, L., & Ashili, S. (2023, June 1). Smart wearables addressing gait disorders: A review. Materials Today Communications. https://doi.org/10.1016/j.mtcomm.2023.106250
7. Kesari, S., Wang, R., Juarez, T., Ashili, S., Patro, C. P. K., Carrillo, J. A. O., Nguyen, M., Truong, J., Levy, J., Sommer, J., Freed, D. M., Xiu, J., Takasumi, Y., Bouffet, R., & Gill, J. (2023, May 5). Activity of pemetrexed in pre-clinical chordoma models and humans. Scientific Reports. https://doi.org/10.1038/s41598-023-34404-4
8. Pingle, S. C., Lin, F., Anekoji, M. S., Patro, C. P. K., Datta, S., Jones, L., Kesari, S., & Ashili, S. (2023, April 1). Exploring the role of cerebrospinal fluid as analyte in neurologic disorders. Future Science OA. https://doi.org/10.2144/fsoa-2023-0006
9. Biswas, N., Chakrabarti, S., Padul, V., Jones, L., & Ashili, S. (2023, February 9). Designing neoantigen cancer vaccines, trials, and outcomes. Frontiers in Immunology. https://doi.org/10.3389/fimmu.2023.1105420
10. Chakrabarti, S., Biswas, N., Karnani, K., Padul, V., Jones, L., Kesari, S., & Ashili, S. (2023, January 28). Binned Data Provide Better Imputation of Missing Time Series Data from Wearables. Sensors. https://doi.org/10.3390/s23031454
11. Patro, C. P. K., Biswas, N., Pingle, S. C., Li, F., Anekoji, M., Jones, L., Kesari, S., Wang, F., & Ashili, S. (2022, December 26). MTAP loss: a possible therapeutic approach for glioblastoma. Journal of Translational Medicine. https://doi.org/10.1186/s12967-022-03823-8
​
12. Chakrabarti, S., Biswas, N., Jones, L., & Ashili, S. (2022, September 26). Role of smartwatches in Diabetes patient care. Lupine Publishers. https://doi.org/10.32474/ADO.2022.04.000185
13. Chakrabarti, S., Biswas, N., Jones, L.D., Kesari, S., & Ashili, S. (2022, August 31) Smart consumer wearables as digital diagnostic tools: A review. Diagnostics. https://doi.org/10.3390/diagnostics12092110
14. Sunny, J.S., Patro, C.P.K., Karnani, K., Pingle, S.C., Lin, F., Anekoji, M., Jones, L.D., Kesari, S., & Ashili, S. (2022, January 19) Anomaly detection framework for wearables data: A perspective review on data concepts, data analysis algorithms and prospects. Sensors. https://doi.org/10.3390/s22030756
15. Lin, F., Ichim, TE., Pingle, S., Jones, LD., Kesari, S., & Ashili, S. (2020, October 26) Mesenchymal stem cells as living anti-inflammatory therapy for COVID-19 related acute respiratory distress syndrome. World J Stem Cells. http://doi.org/10.4252/wjsc.v12.i10.1067
16. Kelbauskas, L., Ashili, S.P., Lee, K.B., et al. (2018, March 12) Simultaneous multiparameter cellular energy metabolism profiling of small populations of cells. Scientific Reports. https://doi.org/10.1038/s41598-018-22599-w
17. Kelbauskas, L., Ashili, S., Zeng, J., et al. (2017, 16 March) Platform for combined analysis of functional and biomolecular phenotypes of the same cell. Scientific Reports. https://doi.org/10.1038/srep44636
18. Kelbauskas, L., Ashili, S., Zeng, J., Mohammadreza, A., Lee, K., Derkach, D., Ueberroth, B., Gao, W., Paulson, T., Wang, H., Tian, Y., Smith, D., Reid, B., Meldrum, D. (2016, July 15) Single-cell analysis of functional heterogeneity dynamics in premalignant progression revealed by combined interrogation of functional and transcriptional phenotypes. Cancer Research. https://doi.org/10.1158/1538-7445.AM2016-LB-027
19. The Physical Sciences - Oncology Centers Network. (2013, April 26) A physical sciences network characterization of non-tumorigenic and metastatic cells. Scientific Reports. https://doi.org/10.1038/srep01449
20. Song, G., Ashili, S., et al. (2013, December 19) Multiple sensor arrays for single cell metabolic analysis. IEEE Xplore. https://doi.org/10.1109/ICSENS.2013.6688453
21. Zhu, H., Zhou, X., Su, F., Tian, Y., Ashili, S., Holl, M., Meldrum, D. (2012, August 6) Micro-patterning and characterization of PHEMA-co-PAM-based optical chemical sensors for lab-on-a-chip applications. Sensors and Actuators B: Chemical. https://doi.org/10.1016/j.snb.2012.07.101
​
22. Kelbauskas, L., Ashili, S., Houkal, J., Smith, D., Mohammadreza, A., et al. (2012, April 5) Method for physiologic phenotype characterization at the single-cell level in non-interacting and interacting cells. Journal of Biomedical Optics. https://doi.org/10.1117/1.JBO.17.3.037008
​
23. Torres-García, W., Ashili, S., Kelbauskas, L., Johnson, R., Zhang, W., Runger, G., & Meldrumb, D. (2012, March) A statistical framework for multipara meter analysis at the single-cell level. Molecular Biosystem. https://doi.org/10.1039/C2MB05429A
​
24. Ashili, S., Kelbauskas, L., Houkal, J., Smith, D., Tian, Y., Youngbull, C., Zhu, H., Anis, Y., Hupp, H., Lee, K., Kumar, A., Vela, J., Shabilla, A., Johnson, R., Holl, M., & Meldrum, D. (2011, February 14) Automated platform for multiparameter stimulus response studies of metabolic activity at the single-cell level. SPIE Digital Library. https://doi.org/10.1117/12.875438
​
25. Ashili, S., Kelbauskas, L., Houkal, J., Smith, D., Mohammadreza, A., Lee, K., Kumar, A., Anis, Y., Paulson, T., Youngbull, C., Tian, Y., Johnson, R., Holl, M., & Meldrum, D. (2011, February 11) A novel method for multiparameter physiological phenotype characterization at the single-cell level. SPIE Digital Library. https://doi.org/10.1117/12.875483
​
26. Astratov, V., & Ashili, S. (2007) Percolation of light through whispering gallery modes in 3D lattices of coupled microspheres. Optics Express. https://doi.org/10.1364/OE.15.017351
​
27. Astratov, V., Ashili, S., & Yang, S. (2007, August 27) Optical transport phenomena in coupled spherical cavities. 9th International Conference on Transparent Optical Networks. https://doi.org/10.1109/ICTON.2007.4296247
​
28. Astratov, V., Ashili, S., & Kapitonov, A. (2007, January) Optical properties of mesoscopic systems of coupled microspheres. PIERS. https://doi.org/10.2529/PIERS060908001922
​
29. Astratov, V., Ashili, S., & Kapitonov, A. (2006) Observation of light propagation via whispering gallery modes in 3-D networks of coupled spherical cavities. Optica Publishing Group. https://doi.org/10.1364/FIO.2006.FTuB6
​
30. Ashili, S., Astratov, V., & Sykes, E. (2006) The effects of inter-cavity separation on optical coupling in dielectric bispheres. Optica Publishing Group. https://doi.org/10.1364/OE.14.009460
​
31. Astratov, V., Ashili, S., Kapitonov, A., & Kanaev, A. (2006 November 20) Integrated circuits of coupled mircospheres for optoelectronics applications. International Conference on Transparent Optical Networks. https://doi.org/10.1109/ICTON.2006.248244
​
32. Astratov, V., Kanaev, A., Ashili, S., & Cai, W. (2005) Circuits of microspheres for applications in integrated optoelectronics and controllable optical delay lines. Optica Publishing Group. https://doi.org/10.1364/FIO.2005.FTuQ1
​
33. Astratov, V., Kanaev, A., Ashili, S., Franchak, J., & Cai, W. (2005) Optical delay lines formed by circuits of spherical cavities with coupled whispering gallery modes. Optica Publishing Group. https://doi.org/10.1364/IP.2005.IThD2
​
34. Sykes, E., Ashili, S., Kanaev, A., & Astratov, V. (2005) Encapsulated microsphere arrays for applications in photonic circuits. Optica Publishing Group. https://doi.org/10.1364/IP.2005.IThD3
​
35. Astratov, V., Franchak, J., & Ashili, S. (2004, December 6) Optical coupling and transport phenomena in chains of spherical dielectric microresonators with size disorder. Applied Physics Letters. https://doi.org/10.1063/1.1832737
​
36. Astratov, V., Franchak, J., Ashili, S., Kanaev, A., Cai, W., & Deng, S. (2004) Optical coupling and transport phenomena in long chains of slightly disordered spherical microresonators. Optica Publishing Group. https://doi.org/10.1364/FIO.2004.FWB1
​
37. Astratov, V., Franchak, J., Ashili, S., Cai, W., & Hasan, M. (2004) Resonant optical circuits based on coupling between whispering gallery modes in dielectric microresonators. Optica Publishing Group. https://doi.org/10.1364/IQEC.2004.IThI1